I am an avid Penpot convert, but from Sketch App, that I have been using since so many years now. I set up a system so we can install Penpot in no time self-hosted in house, including dns setup and ssl certificates. There are still some rough edges on Safari, such as text not displaying in place, so I may switch to Chrome or Brave for it.
I just wrote a blog post on how to install it here: https://blog.setip.io/foss-subscription-savings/