But interestingly also a very high genetic factor with 90% of identical twins both having T2DM (which is greater than that of type 1 which if I remember correctly is 40%)
Sounds like Nature vs nurture to me. Until there is a proposed genetic marker... it's just another item confusing the public about correlation vs causation.
Looked at the first paper. I have significant concerns that, frankly, I didn't finish reading.
1. Small sample size, <20 iirc.
2. No control group at all. (There should have been a group under the same requirements and same diet)
3. They picked 'uncontrolled', and from my own experience that term is synonymous with "unmanaged." Which, translates to "patient is not compliant with treatment." As such, feeding them exclusively a vague "diabetic diet" coupled with the 5 day hospital stay- well its enough to cloud the results enough that no conclusions can be made.
4. Cont. Because people rarely intentionally make themselves feel like crap- which you will with uncontrolled type II. The hospital stay, its exposure to allegedly* diabetic friendly foods, and subsequent time for the subjects to realize "I feel better, I like this!" Basically invalidates the entire paper.
* allegedly, because I just got out of a hospital with a fantastic cafeteria. But, the "diabetic menu" had way to many items with high glycemic indexes, and nothing to maintain a steady sugar level until the next meal.
Finally:
''HbA1c was lower four weeks after the oatmeal intervention.''
The soil in the Austrian Country of Styria has notoriously low iodine levels. When visiting Styria in 1748, David Hume wrote:
'But as much as the country is agreeable in its wildness, as much are the inhabitants savage, and deformed, and monstrous in their appearance. Very many of them have ugly swelled throats; idiots and deaf people swarm in every village; and the general aspect of the people is the most shocking I ever saw.' [1]
That's why some traditional costumes in that region include a so called "Kropfband" (goitre bound). [2]
It's fascinating how much one's place of birth used to influence a life and medical biography and in many countries still does.
I put a lot of hours into SupCom. It was always a buggy mess, but I do remember it quite fondly. Planetary Annihilation has felt like the right progression in the spiritual series. It was always a very smooth experience and fixed the technical issues with scaling up to massive scale combat while fixing the balance issues of turtling. The skill ceiling is immense and I could never beat high level bots. The nature of having one to many planets also means you can play cooperatively with up to several friends. It's a good time.
That's technically true. Planetary Annihilation was a heroic effort lead by Jonathan Mavor (formerly of Gas Powered Games) that fused elements of TA, SC, and its own crazy ideas on what amounted to a shoestring budget.
Supreme Commander's budget was about $50M USD (circa the mid-2000s), and Mavor was lead engineer on the project.
Beyond All Reason is arguably more similar to Total Annihilation than Planetary Annihilation.
By that same token, Sanctuary is the closest thing to a complete remake of Supreme Commander. Granted, Forged Alliance Forever has had such incredible work put in by the community that it comes close, but it's ultimately stuck on the same engine.
Turns out Mavor has a new company now, and I'm elated to hear someone's finally combining Factorio with a decent RTS component:
LineageOS, CalyxOS and GrapheneOS all come with Seedvault which allows nightly remote backups. They're anything but complete, though. For folders, Syncthing might be interesting. I don't think it's possible without rooting your phone. Then, NeoBackup could do it.
Thanks. I looked into Seedvault and gather one of its challenges is a reliance on API's that are deprecated and (in the meantime) becoming intentionally degraded. Eg. Apps can exclude themselves via android:allowBackup=false.
There have been calls to modify Seedvault to impersonate D2D transfer in order to bypass the restriction. Or I wonder if I can patch the OS to ignore/override that app manifest flag? (I gather some people are patching their APK's).
With 7 Watts, the Snapdragon has less than half the Intel's and Apple's TDP, though. Also, the i7-1355U only became available in 2023.
The confirmed upgrades to 8 performance cores (from 4), ARMv9, PCIe 4, DDR5 RAM and possibly a higher TDP will bring significant performance gains with Gen 4.
But in principle I agree to you, I wouldn't use it yet.
