Where are we in the hype cycle regarding microbiome? Would it be feasible to launch a startup that leverages the synergy between AI, the blockchain and gut bacteria? I am serious!
It does feel like every organ system and every disease has at least one research group trying to connect it to the microbiome. It's reminiscent of the hype cycle around oxidative stress and antioxidants 20 uears ago. There was a core of solid science there, but in terms of connecting specific diseases to oxidative stress, it seems like the research community has largely moved on.
> in terms of connecting specific diseases to oxidative stress, it seems like the research community has largely moved on.
As someone who knows someone at UNC Chapel Hill who was researching this starting about 15 years ago, the research community did not move on, the news just stopped talking/hyping about it.
Here is a recent paper:
Oxidative stress: The core pathogenesis and mechanism of Alzheimer's disease
It is fundamentally true that oxidative balance is crucial to health, and that nutrients play a large role in maintaining that balance; Manganese (SOD2) zinc/copper (SOD1/SOD3), Selenium/Riboflavin/Pyridoxine (Glutathione).
Deficiencies will not cause one disease, but many different ones, depending on the persons risk.
I think oxidative balance plays a large role in controlling the microbiome.
Nutrition, oxidative stress and intestinal dysbiosis: Influence of diet on gut microbiota in inflammatory bowel diseases
If you were a nonprofit medical service or a for-profit insurance company, you could do AI analysis of gut microbiome eDNA against electronic health records with potential for significant value if you could get a stool sample every so often.
> Ani Biome uses machine learning models to provide personalized solutions for enhancing gut microbiome function and addressing inflammation, a prevalent factor in age-related chronic ailments.
