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Thats https://en.wikipedia.org/wiki/Withdrawal_reflex

The "decition" is made by the spinal cord. It's not surprising if you imagine that the brain is an oversized part of the spinal cord.

See also https://en.wikipedia.org/wiki/Ganglion


So if it’s known decision making, so to speak, was happening via electrical signals in the spinal cord… why is it suprising that it happens in other types of cells too?

Someone replied to me in an old comment that for fast Python you have to use numpy. In the folder there is a program in plain python, another with numpy and another with numba. I'm not sure why only one is shown in the data.

Disclaimer: I used numpy and numba, but my level is quite low. Almost as if I just type `import numpy as np` and hope the best.


For what it's worth, I've ported a lot of heavily optimized numpy code to Julia for work, and consistently gotten 10x-100x speedups, largely due to how much easier it is to control memory allocations and parallelize more effectively.

> Almost as if I just type `import numpy as np` and hope the best.

As do we all. If you browse through deep learning code a large majority is tensor juggling.


One problem is people selling their home to pay for snake oil, so their children now are not only orphan but also homeless.

Imagina an evil bank clerk on the door of a cancer center that says:

fake quote> There is a new promising [unverified] treatment that can save the life of your S.O. It's very expensive so you have to take a double mortgage on your home. You are very lucky, because today we are offering it with only a 49.99% interest rate. Do you love him/her?


Okay great point I hadn’t considered - makes the parent comment more sensible. Thanks!

Two minor complains:

Why the bell off is sliced? https://www.itshover.com/icons/bell-off-icon

Why the refresh icon rotates in the wrong direction? https://www.itshover.com/icons/refresh-icon


If you see a very strange pattern, you can send an email to hn@ycombinator.com so dang/tomhow can take a look.

As the other comments say, there is a lot of spam that is detected automatically and manually. You can take a look at https://news.ycombinator.com/newest with "showdead" enabled. While you are there, remember to upvote good post and flag spam.


It's very confusing that the letters move a little when I click on them. I think they should not move until I select an action on the right.

Clicky https://fusion-circus-ultimate.vercel.app/

After the tutorial finish, the stability slowly decrease, and it's not clear what I can modify.

After a while, I found that I can turn on one of the slides on the right, but I have no idea why it's useful. It would be nice to continue the tutorial until I have to turn on/off the slides a few times.


Sure, I’ll polish the tutorial, each device on the top left is correlated to its rightful tools in real life, so some tool functions may be darkened preventing you from using it, unless you turn on the R&D mode or Frontier mode. Right now the tutorial is meant for the 1st 9steps but soon will be more! You’ll be the first to know! thanks for the feedback! Appreciate it! I’ll get to it asap!

Do you have an English translation? Post in other languages never get traction here, unless there is no similar post in English. And I guess this has been covered by a few English sources.

Do you still have a video saved somewhere?

> The results demonstrated the therapy not only reduced tumour size but also entirely stopped tumour growth with no evidence of tumour resistance for more than 200 days after treatment.

More details in https://www.pnas.org/doi/suppl/10.1073/pnas.2523039122/suppl... See page 25

In mice, N=12.

1 survived 200 days without cancer and was euthanized for 'ocular ulcers'.

5 survived 50-150 days, without cancer but were euthanized for other health problems

6 survived 50-150 days, and still had a smaller tumor and were euthanized for other health problems

My take away: Interesting, but the press article is overselling the result by a lot.

Edit: Fixed link.


So: half (1+5) of them made it at least 50 days without cancer, and the other half made it at least 50 days with a smaller tumor? This sounds excellent to me. I agree that the sentence you quoted is overselling, though.

Mice are very short-lived compared to us. In humans, the usual standard of judgment when it comes to cancer is "5 year survival". No mouse has ever lived for 5 years yet, that would be like 180 years for us.

Prolonging a mouse's life by a few months is non-trivial and hints (only hints) at potential efficiency of such treatment in other species as well.


Apparently 50 mice days is equivalent to about 5 human years, so even if these other causes of death here directly caused by the treatment (not alleged), surviving this much longer (5-20 years) would be pretty incredible for humans.

Where did you get that "50 mice days is equivalent to about 5 human years"?

Mice are short lived, so the time for some events like sexual maturation are shorter.

On the other hand, the problem with cancer is that it adapts, it "learn" how to avoid the effect of the drugs, or how to make the signals to get more blood vessels, or ... I think most of these only depend on how many times the cancer cells reproduce to get a lucky adaptation, so for these effects 200 days is only 200 days.

Also survival rate depends on how early it's detected. In a recent post about colon cancer, the mice got the treatment like 2 weeks after the cancer cells were injected. My guess is that this study also has a short time before the treatment.

Early detection improves survival rate a lot: https://www.cancerresearchuk.org/about-cancer/pancreatic-can...

> Localised: More than 25 out of 100 people (more than 25%) survive their cancer for 3 years or more after diagnosis.

> Regional: Around 15 out of 100 people (around 15%) survive their cancer for 3 years or more after diagnosis.

> Distant: Only 1 out of 100 people (1%) survive their cancer for 3 years or more after diagnosis.*

Also (combining all detection stages):

> Generally for adults with pancreatic cancer in the UK:

> around 5 out of every 100 (around 5%) survive their cancer for 10 years or more


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