I'm in a very similar situation to yours and have lived in SF for past 2 years now. Initially, I was buzzing with excitement, however now I want to leave for a less busy place (kind of "we all want what we don't have situation"). My advice is go for it, just don't get your self stuck with long term rent or other contracts. You'll likely want to live elsewhere for a few months as a "detox" from SF and then come back.
Regarding meditation, there is amazing app called Headspace that can get you calm relatively fast. I also use this one trick that immediately releases the tension: Sit down somewhere quiet, inhale deeply and on your exhale let your jaw, shoulder, back muscles fall down. We carry a lot of pressure in these and subconsciously forget to relax them.