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I have a new casino idea.


You should call it rat race ;)


Time to revisit Mitchell and Webb’s brilliant immortal kids skit



Chrome and Firefox’s reading list is perfect for this purpose


I tried using Safari's reading list for this long ago, but it's too out-of-sight, out-of-mind and stuff went in there to be forgotten about. Tabs and windows are in my face cluttering up my screen the whole time, begging to be finished.


It's more hassle than middle-click to open something I plan to read in another tab.


I still don't understand why these can be sold in American pharmacies.


They're even covered by some insurance plans.

A friend of mine is an orthopedic surgeon, and they explained to me that for mild problems, which would normally heal on their own, it's cheaper to cover a placebo rather than real medication.


While I hear this argumentation a lot, I still struggle with this:

If you have "mild problems, which would normally heal on their own", buying no medication at all would be even cheaper.

And from an ethical point of view, the idea of financing a whole (homeopathic) industry that uses your money to produce fake science, even with a single cent, should make one shudder, shouldn't it?


> If you have "mild problems, which would normally heal on their own", buying no medication at all would be even cheaper.

But placebos actually outperform no intervention.


Okay, fair point.

But then, why prescribe the most expensive placebos where you co-finance societal harmful behavior, rather than just prescribing the "harmless" placebos that are not homeopathy, which are usually even cheaper and don't have any ideological overhead?


I'm not aware of any research along these lines, but I suspect that all placebos are not equally effective.

It's a psychological effect, so things like price or flavor or packaging likely affect its strength.


Yea there is research into it, and you're correct

Color matters: placebo colored pills work better than white pills.

Delivery mechanism matters: placebo injections work better than pills.

Idk about price, packaging, or flavor specifically. But delivery mechanism, color, number of pills, etc I remember from a study.


The 2008 Ignobel Prize in Medicine was awarded for a paper that showed that higher-priced placebos are more effective than lower-priced placebos [0].

[0] https://en.wikipedia.org/wiki/List_of_Ig_Nobel_Prize_winners...


I think it comes from our animistic roots. Magic that calls for the sacrifice of a goat is stronger than magic that calls for the sacrifice of a flower because the former requires more dedication from the caster. It would be the same with money.


There is a lot of over-the-counter and even some prescription medicine that don't do much at all for what people take them for, and homeopathy is cheaper and less harmful for the same placebo effect. Cold medicine in particular is known for its dubious efficiency.

No medication is even cheaper, but the placebo effect works, so if people were to take something, might as well have them take something cheap and harmless. In my opinion, it doesn't justify supporting homeopathy, but health insurances may see it differently.

Placebos are an interesting ethical issue. Doctors are not supposed to deceive you, they are people you trust with your life and very personal issues and they are therefore held to very high standards. But even if it is for your own good, the placebo effect is based on deception, so is it ethical for a doctor to give you a placebo? And is fake science that still help people ethical? The consensus seems to be "no" for both and I tend to agree, but I still think it is worth debating.


Here we have an article that claims that even when people are told they are getting a placebo, they still felt better after taking it.

https://www.health.harvard.edu/blog/placebo-can-work-even-kn...


> If you have "mild problems, which would normally heal on their own", buying no medication at all would be even cheaper.

American culture loathes the idea of not treating a disease. Problems are expected to be dealt with, even if it harms society (see overprescribing antibiotics or opioids).

When confronted with people that don't understand the impacts of medicine, it's easier for an insurance company to give them fake medication than nothing at all.


To those who downvoted: Would you dare to explain your disagreement?


Indulging without argument a patient's harmless fantasies economizes on physician time, and that is surely the most precious resource.


This is basically how TCM came to be!

The Chinese Communist Party had billions being raised out of incredible poverty and that populace started demanding medical care. There was no possible way to supply enough clinics, doctors, nurses, etc - and not just because Mao whipped the Red Guard into an anti-intellectual froth than then slaughtered much of China's academic/scientific community.

So Mao waved his hands and invented TCM, which basically said "oh yeah, most of these traditional Chinese medicines work. We did some research and figured out which ones and how to apply them!"

Hilariously people argue TCM doesn't work not because it's complete bullshit, but because it's a modified, corrupted version of actual Chinese medicine...


Sometimes I get into conversations with TCM advocates.

"If you get into a car accident in China," I say, "an ambulance will take you to a hospital where they will treat you with western medicine. Why do you think that is?"


It’s even cheaper to offer nothing. Some humans are just quite something.


In France they were funded by the social security up to 15%, but luckily this stopped in 2021. I had some as a kid and my mom is still a strong "believer" in them. I don't see any harm in selling them IF and only if they don't prevent people from taking other "real" treatments. But other than this it's just placebo.


> and only if they don't prevent people from taking other "real" treatments

This is the dominant harm, yeah. As we know from infosec, few things are more dangerous than a false sense of security, and that's exactly what ineffective drugs provide.


Most of homeopathy usages target little aches and whatnots that require no treatment (beyond patience), so I guess it could also act as a buffer against overmedication.


Because every bottle is clearly labeled “The FDA has not evaluated this for treating any condition”. There are a great many products that the FDA hasn’t evaluated that are still sold, why should these be any different?


It's the other way around, the 'FDA has not evaluated' text is indicating that these products are different and part of a special loophole created just for them: https://en.wikipedia.org/wiki/Dietary_Supplement_Health_and_...

The reason that these get to make health claims and stuff without regulation, and get special treatment, is lobbying resulting in that act. Otherwise they would have been regulated.


But why are businesses like CVS hawking snake oil while also having trained pharmacists on staff.


Most pharmacies used to sell tobacco products (they only started to do so after a couple of states started banning the practice.) Walgreens still does (in states where it isn't banned from doing so).

https://www.beckershospitalreview.com/pharmacy/walgreens-tes...

> "The safety of our patients is very important, but we also have to do what our customers are requiring us to do," Walgreens CEO Stefano Pessina told the WSJ. "We see that when we don’t sell tobacco, we have a lot of [negative] reactions."


It makes money


Because a lot of those bottles also make claims that are in violation of the FDA rules. The label is not sufficient.

They need to avoid making claims that they can treat or diagnose some condition. They do their best to hint at it without crossing the line, and frequently blatantly do cross it. The FDA does not have anywhere near the manpower to enforce it. And when they do finally get around to it, the brand vanishes, and a new one appears with exactly the same product lineup.

The sector has long lost any entitlement to benefit of the doubt. They are knowingly making illegal claims and using a disclaimer as a fig leaf even though everything else on the package contradicts it.


It's not illegal and its not in violation of FDA rules. That disclaimer text is from a specific law that gives them exemption from those rules: https://en.wikipedia.org/wiki/Dietary_Supplement_Health_and_...

It's not a manpower issue, it's not a legal issue. It's not against the law because they wrote the law. There is no line they try to avoid crossing because that line was erased by lobbyists in 1994.


As I said, it's not the disclaimer. It's all of the other text that contradicts it.


Because they are not labeled as medical products. It is a loophole.


What should not be allowed to sold in pharmacy? Or should that even be asked. I think this is pretty relevant question. Should pharmacies have some extra regulation that limits them from selling anything but exactly approved products? Or specific models of such? Like only certain toothbrushes?


Well, the placebo effect is real so the products do actually work. Weird line, sure, but still.



THE PLACEBO EFFECT:

It works even when you know it's a placebo.


This is an incorrect summary of the placebo effect. The placebo effect does require the patient to either believe it is effective, or at least not knowing clearly it is ineffective.

This is why clinical studies don't tell neither group (neither the treated group nor the control group) who is in which group, to not spoil the results.

And also, this is why homeopathy puts so much effort into spreading the belief they are effective despite all odds, up to the point of trying to convince people to abandon basic scientific principles.


GP is actually correct according to Wikipedia[0] (for what that's worth): There seems to be evidence that "open-label placebos"—i.e. "where the patient is fully aware that the treatment is inert"—still have positive effects.

[0] https://en.wikipedia.org/wiki/Placebo#Effects


Contrast this with advertisement, which actually does work even when people know that it is ads, and which still does work on people how know how ads work.

Also, contrast this with psychotherapy, which usually does work even better if the patient understands how it works, because it enables them to become an active and more effective part of the therapy.


studies don't tell you about being on a placebo because of blinding, not because it would stop the placebo from working.


They couldn’t. But then a law called the DSHEA was passed that changed all the rules.


Aren’t they normally sold as supplements’ not medicines, to circumvent regulations?


They are powerful placebos, so the believers have become permanently duped.


Placebos work even if users know it's a placebo. I don't for a second believe in any of homeopathy claims, but I still buy and use it, because placebo works. Especially so when price and all other medicine-looking rituals around it are maintained.


It's considered a dietary supplement, which is governed by the dietary supplement health enforcement act, which in turn classifies dietary supplements as a food product.


Very much false.

1. Under the Federal Food, Drug, and Cosmetic Act, homeopathic products are subject to the same requirements related to approval, adulteration and misbranding as other drug products. https://www.fda.gov/drugs/information-drug-class/homeopathic...

2. Homeopathic products are "classified as either over-the-counter (OTC) or prescription medicines." https://www.chpa.org/about-consumer-healthcare/faqs/faqs-abo...


from that same link:

> There are no FDA-approved products labeled as homeopathic; this means that any product labeled as homeopathic is being marketed in the U.S. without FDA evaluation for safety or effectiveness.


That's beside the point of the comment I replied to, which falsely said homeopathic products were classified as dietary supplements.


I for one am glad they they sell clean water in pharmacies, and support its continued sale!


People want to buy them and we live in a free country.


Unless we want to make people accountable for running their own sophisticated clinical studies for every single product we buy, we should probably have some rules in place around false claims and false advertising.


We have those rules about how homeopathic "medicine" can be labeled.

At the end of the day, people are allowed to buy dumb shit. 50% of my local CVS is make-up, which is way more egregious than echinacea root extract.


Yes but it’s clearly not good enough


Maybe we should also have some rules around false claims and false advertising around food in general. I think this causes more damage than homeopathic stuff ever can do.


I might be downvoted for this, but I tend to have a kind of libertarian take on this. I absolutely do not believe in homeopathy beyond placebo effects, and I understand the harm they do by opportunity costs in pursuing other treatments.

But at the end of the day I feel like all medications should basically be handled like homeopathy products. They should be available to anyone, barring some kind of competency ruling or disagreement by the pharmacy over what they want to sell to whom, and the FDA should basically ensure that they are what they say they are on the label.

I'm glad there's skeptics out there calling BS on homeopathy but where I diverge from them is in somehow preventing it from being available. It's water, it's labeled accurately, so let people do what they're going to do. If they weren't doing this I doubt they'd be doing something more "mainstream" anyway, or complying with it. They might even be doing something even more actively harmful.

I guess I see it as a slippery slope from banning homeopathy to something much murkier where reasonable experts disagree. Real medical science can get very grey really fast and I'm not sure I trust regulatory authority figures to always make the best decisions about what to do. Better to leave it to the consumer and whichever provider they trust most.

Demand product purity, prevent health claims on the label, whatever, but I think my question is "why aren't more medications sold in American pharmacies?"


its not about banning availability, its about making them required to prove the health claims theyre making. If you didn't have any requirements to prove your drug worked before selling it, youd take away a pretty huge market incentive to make drugs that work (health is about as far from a perfect full information free market as you can get -- homeopathy doesn't work at all and those companies are making plenty of money). These regulations also force research into and labeling of side effects, and skimping on that led to an opiod crisis.

Honestly don't really see the economic or societal argument for deregulating medicine. If you want a system where to get an fda stamp you have to prove it works but can sell whatever otherwise with no consequences until you kill someone or destroy their gallbladders (https://www.foodsafetynews.com/2024/05/fda-determines-that-t...) - well that's what we already have now so given it hasn't changed in decades, even with recent attempts to do so after all the strip mall stem cell clinics and GRAS issues and all, I don't think your opinion is that out of the mainstream.

And in terms of why aren't more sold in pharmacies - no clue what you're talking about there lol. Have you not seen the A-Z supplement whatever aisles full of all this unregulated crap? You can buy whatever you want unless the DEA has an issue with it.


> You can buy whatever you want unless the DEA has an issue with it.

Over the counter? No, you can't. You can buy a lot of stuff that doesn't work over the counter. But, for example, if I want a decongestant that actually works (pseudoephedrine HCl), I have to go to the pharmacy and show them my driver's license and make a record of the purchase because the government is afraid I might start a meth lab.

And that doesn't even get into all the market failures with prescription drugs. What if I have the same bacterial infection for the umpteenth time and I know that antibiotic X will fix it? Can I just walk into the drugstore and get a course of antibiotic X? Of course not. (At least, not in the US. But in Mexico, I can.)

Even if the argument is that I might be misdiagosing my symptoms (which, if it's the umpteenth time I've had the same thing, is not a very good argument), why isn't there a machine in the drugstore that can check my diagnosis? It's already been shown that expert systems can outperform human doctors for many diagnostic tasks. In a functioning market for health care, we would see that technology in wide use. But we don't, because we don't have a functioning market for health care.


pseudoephedrine - you can't buy that because the DEA has a problem with it lol.

and you can buy the other stuff as reagents/third party suppliers etc, for 'research' use.


> pseudoephedrine - you can't buy that because the DEA has a problem with it lol

Ok. (Though there is still the question of whether it actualy makes sense for the DEA to care.) How about commonly used antibiotics?

> you can buy the other stuff as reagents/third party suppliers etc, for 'research' use.

Antibiotics? Please enlighten me.


for cell culture lol it's not hard to find them, even though arguably it should be because of resistance. Also this isn't advice to take them - they aren't regulated and so you shouldn't trust them lol they're for research use only for a reason


> this isn't advice to take them - they aren't regulated and so you shouldn't trust them lol they're for research use only for a reason

In other words, no, I can't buy anything I want unless the DEA has a problem with it. I can buy stuff that doesn't work or that I can't trust, but I can't buy antibiotics (or many other things I might want) that I can trust. Which of course concedes my point.


You don't have a right to buy stuff that works or that you can trust, the point is that for noncontrolled nonpatented substances, nobody can stop you from buying or synthesizing active ingredients for your own use in the US, even if logically you shouldn't be trusted to have the competence to not hurt yourself, or if frankly there should be way way more regulation.

You keep bringing up antibiotics but it's the category of drugs with the most widespread use (animal agriculture) with one of the strongest cases for being drastically under-regulated - they stop working if things become resistent to them and we spray them everywhere like candy. Also you keep acting as if getting a prescription is some sort of actual barrier or burden for non-prescription drugs, which is particularly funny after the whole fiasco with wegovy off label prescriptions before the active ingredient was approved for obesity/launched for obesity. These are not real barriers, even when they probably should be.


> it's the category of drugs with the most widespread use (animal agriculture) with one of the strongest cases for being drastically under-regulated

To call this area "under-regulated" is not accurate: the whole food production chain in the US, with all of its dysfunctionality, is a product of decades of regulation and government interference and mismanagement. The best way to stop antibiotic use with animals is for people to stop eating meat and other products from those animals, and if anything is going to facilitate that, it's going to be the market, which is already providing plenty of products in grocery stores that are from animals raised with no antibiotics, and will provide more the more people choose to buy them, as I do.


> You don't have a right to buy stuff that works or that you can trust

We're not talking about rights here. You claimed, and I quote, "You can buy whatever you want unless the DEA has an issue with it." I am simply pointing out that that is not true. Whether it should be true as a matter of right is irrelevant to that factual question.

> you keep acting as if getting a prescription is some sort of actual barrier or burden for non-prescription drugs

Um, no, I said no such thing. Obviously having to get a prescription is not a barrier or burden for non prescription drugs. But, as you yourself have pointed out, a huge number of those non-prescription drugs, for which there is no barrier or burden, don't work. And, as you have also pointed out, routing around things like prescriptions to get, for example, antibiotics means you can't trust the product. So there are barriers and burdens in the way of getting things that do work and can be trusted. Which was my point, and which contradicts your original claim that I responded to.

The question of whether there should be all these barriers and burdens in the way of buying things that work and can be trusted is a separate question. Your argument for why there should appears to be that without such barriers more harm would be done. Of course there will always be people who make stupid choices, and giving people more freedom by removing barriers and burdens will increase that. But you are not recognizing the other side of the barriers and burdens, which is that they prevent people from making good choices, choices that could save their lives. For example, look up the harm done in preventable deaths by the FDA's slowness in permitting beta blockers.

The post you responded to that advocated a libertarian approach was saying, in effect, that, on net, the harm done by regulation is greater than the harm done by individual people making bad choices in the absence of regulation. I happen to agree. You apparently do not. But I do not see that you have given any reason to believe that the opposite is true. I certainly don't see anything in what you've posted that makes the opposite claim the slam dunk that you appear to think it is.


When i said buy whatever you want, i was referring to the ingredient in the drug, which you can buy or make with no issues.

And when i say the prescription not being a barrier, i'm not talking about not needing a prescription to get research grade antibiotics. I'm talking about how needing a prescription to get a non-controlled drug is literally a non-issue because of rampant off label prescribing and online prescription mills.


At this point your use of the Humpty Dumpty principle makes further discussion highly unlikely to be fruitful.


If the homeopathic remedies don't harm anyone (I know that some have, this comment only references the remedies that don't), what is the problem with them being sold and used?

Many cold medicines have side effects, some are even abused recreationaly. Given that human bodies tend to recover with or without cold medicine (and given the shaky legs that Phenylephrine stands on), what is the issue with people using "fake medicine"?

Homeopathic remedies cannot be abused recreationaly. They aren't precursors to meth. They are better in every way (except the don't work better than a placebo). But, if all a patient needs is a placebo (people recover from the common cold just fine without medicine), homeopathic remedies are perfect.

Remember the hippocrattic oath: First of all, do no harm. Safe, well prepared homeopathic remedies shouldn't do harm. Many cold medicines do.


Why not just prescribe a crystal and some essential oils instead? Maybe have them sacrifice a chicken tomorrow evening at dusk? Actually, if they send me $400 in Bitcoin I will simply cure them with the power of prayer. Nobody is making meth off of my well wishes either.


> Actually, if they send me $400 in Bitcoin I will simply cure them with the power of prayer.

Sounds like a business plan


Why a prescription? If the patient can get a placebo fix without a prescription, isn't that better?

Of course having a "healer" present with a "prescription" may make people feel better. So maybe prescribing crystals is better than pharmacy homeopathic remedies.

However, none of this needs to cost $400. Given that these are all placebos, they should cheap and safe.


Nah, if they need to believe in homeopathic cure-alls it most definitely needs to cost $400. Compared to a Medbed, I'm offering a total bargain.


> what is the issue with people using "fake medicine"?

Because people are being tricked into thinking they’re taking medicine, preventing them from seeking out medical care.


The choice is

over the counter cold medicine

vs

homeopathic "remedies".

Neither of these cure diseases. Neither of these prevent the seeking of medical care. Both of them may make people feel better (the placebo effect can be powerful). Only one of these is frequently abused by teenagers as a recreational drug.


There are plenty of people who take homeopathic and other alternative products instead of prescription products because they can't afford the prescription products, and fraudulent advertising makes them think the alternative is more or less equivalent.

I actually had someone at a pet store try to sell me homeopathic medication instead of dewormer because they were out of actual dewormer. Do you think that's harmless to someone who doesn't know the difference between giving their pet real medication vs. magic woo water?


Your appendix is about to burst, the surgeon is busy, but do some yoga near this crystal and it’ll clear right up


> There are plenty of people who take homeopathic and other alternative products instead of prescription products because they can't afford the prescription products,

True

But worse people use homeopathic remedies because they do not trust modern medicine

Harmless for cold cures, not harmless for infectious diseases


I'm only advocating for homeopathic cold medicine. Real cold medicine does not cure the common cold and does have harmful side effects.

Your examples are cases where homeopathic remedies should not be marketed beside real medicine.


>“hackers” might “contact my family” to, what, send them thousands of photos of my dog??

I'm confused. The attacker doesn't have access to the author's photos or family contacts, right?


They don’t. They’re using another phone and texting the original owner, threatening them, in order to scare them into unlocking the device.

When you boot the “Lost” phone, it asks for the password of the owner’s iCloud account. There is probably an information leak where the original email or phone is presented and the thief can track the original owner through that.


The original iCloud email address is partially obfuscated “eg. e***@icloud.com”, so it’s unlikely to be useful.

For this, they’re most likely reading the phone number from the physical SIM card left in the device.



I use my 3B solely for adblocking via Pi-hole and it works fine most of the time


R Pi in a nutshell. Three sigma and proud of it! :)


Cool game. Would be nice if entering a wrong answer clears the input field so it doesn't need to be cleared manually. The wrong answer can be moved to a history guesses list elsewhere so the player doesn't need to memorize their past attempts.


The demo containers and their animation are so cool and useful.


Is it just me or does selectcommitteeontheccp.house.gov have a very suspicious design including stress-inducing red and black colors, weird layout, low-res header images, and "Click HERE" links that look like social engineering?


It’s not just you. That site is not consistent with any other US gov design language. It also looks cheap and like a QAnon conspiracy news site.


Time to wishlist those strawberries


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