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One place where I ran into this was when I was building an ETL framework in Scala. The scenario was that I wanted to be able to move data from one database system to another and not have the end user of the DSL have to care about the types. The use case was essentially that you should be able to show up to an arbitrary database, run a query, and then pump that output somewhere else (e.g. another DB, flat file, transformation function, etc...)

I went around in circles and ultimately concluded no amount of type inference or other things in Scala's bag of tricks would let a user of the API avoid the dreaded type cast.

I have often seen this situation whenever I have tried to write generic code in a static language that needs to interact with a database.

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That sounds like a perfect use case for type classes, have you tried that? If so, I'd be interested to know why it failed, if you can find the time.

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Syapse Inc -- Palo Alto, CA & Philadelphia, PA

Role: Senior Customer Solutions Software Engineer (Python/JavaScript)

Be a part of a team helping to cure cancer, stop heart disease, and deliver the right drugs to the right people at the right time with software for precision medicine.

Syapse software helps healthcare providers use next-generation genomic and molecular data, in context with complex clinical data (medical history, treatment, outcomes, etc.) to make the best decisions regarding patient care.

See here for all the open positions: http://syapse.com/about/careers/

I'm especially looking to hire a Senior Customer Solutions Software Engineer for the Philly office (http://syapse.com/about/careers/openings/?gh_jid=32512). So if you're on the East Coast and always wanted to join a Bay Area startup, but didn't want to relocate, now is your chance!

We're especially interested in people with Python experience. Any experience with healthcare, electronic health records, or genomics is a bonus.

Learn more about what we're doing from our presentation at AWS re:Invent: http://www.syapse.com/blog/aws-reinvent-video-and-slides-now...

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Syapse Inc -- Palo Alto, CA & Philadelphia, PA

Roles: Customer Solutions Software Engineer (Python/JavaScript), Customer Solutions Project Manager

Be a part of a team helping to cure cancer, stop heart disease, and deliver the right drugs to the right people at the right time with software for precision medicine.

Syapse software helps healthcare providers use next-generation genomic and molecular data, in context with complex clinical data (medical history, treatment, outcomes, etc.) to make the best decisions regarding patient care.

See here for all the open positions: http://syapse.com/about/careers/

I'm especially looking to hire Customer Solutions Engineers for the Philly office (http://syapse.com/about/careers/openings/?gh_jid=32512). So if you're on the East Coast and always wanted to join a Bay Area startup, but didn't want to relocate, now is your chance!

We're especially interested in people with Python experience. Any experience with healthcare, electronic health records, or genomics is a bonus.

Learn more about what we're doing from our presentation at AWS re:Invent: http://www.syapse.com/blog/aws-reinvent-video-and-slides-now...

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"Never" is a pretty log time. Curious what reasons you have for making that statement?

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physics

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Syapse Inc -- Palo Alto, CA & Philadelphia, PA

Roles: Customer Solutions Software Engineer (Python/JavaScript), Customer Solutions Project Manager

Be a part of a team helping to cure cancer, stop heart disease, and deliver the right drugs to the right people at the right time with software for precision medicine.

Syapse software helps healthcare providers use next-generation genomic and molecular data, in context with complex clinical data (medical history, treatment, outcomes, etc.) to make the best decisions regarding patient care.

See here for all the open positions: http://syapse.com/about/careers/

I'm especially looking to hire Customer Solutions Engineers for the Philly office (http://syapse.com/about/careers/openings/?gh_jid=32512). So if you're on the East Coast and always wanted to join a Bay Area startup, but didn't want to relocate, now is your chance!

We're especially interested in people with Python experience. Any experience with healthcare, electronic health records, or genomics is a bonus.

Learn more about what we're doing from our presentation at AWS re:Invent: http://www.syapse.com/blog/aws-reinvent-video-and-slides-now...

-----


Syapse Inc -- Palo Alto & Philadelphia, PA

Roles: Customer Solutions Software Engineer (Python/JavaScript), Customer Solutions Project Manager

Be a part of a team helping to cure cancer, stop heart disease, and deliver the right drugs to the right people at the right time with software for precision medicine.

Syapse software helps healthcare providers use next-generation genomic and molecular data, in context with complex clinical data (medical history, treatment, outcomes, etc.) to make the best decisions regarding patient care.

See here for all the open positions: http://syapse.com/about/careers/

I'm especially looking to hire Customer Solutions Engineers for the Philly office (http://syapse.com/about/careers/openings/?gh_jid=32512). So if you're on the East Coast and always wanted to join a Bay Area startup, but didn't want to relocate, now is your chance!

We're especially interested in people with Python experience. Any experience with healthcare, electronic health records, or genomics is a bonus.

Learn more about what we're doing from our presentation at AWS re:Invent: http://www.syapse.com/blog/aws-reinvent-video-and-slides-now...

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I've made my fair share of hairball networks over the years. but I don't think this fixes the issue. The problem is that biological network diagrams of sufficient detail to be accurate, are far too complicated to be useful. Plus, biologists are often sloppy with their data model for these things: mixing genes and proteins for example. In those cases, what does a line between two nodes even mean?

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If you have a complicated system, the best way to deal with the complexity is to organize it in some fashion. BioFabric provides a way to do that, since it allows the network to be arranged in a linear fashion. Kinda like the advantages of organized adjacency matrix views, but with the intuitive link-hopping model of node-link diagrams. I can't argue that if you put garbage data in, you get garbage out. But, over time, very large but high-quality biological networks will emerge.

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Syapse Inc -- Palo Alto & Philadelphia, PA

You can build advertising networks, make tools for financial institutions, help retailers target buyers...the options are endless. But are you excited by any of these choices?

There is another option: you could be a part of a team helping to cure cancer, stop heart disease, and deliver the right drugs to the right people at the right time with software for Precision Medicine.

Syapse software helps healthcare providers use next-generation genomic and molecular data, in context with complex clinical data (medical history, treatment, outcomes, cost, etc.) spread across multiple systems, to make the best decisions regarding patient care.

See here for all the open positions: http://syapse.com/about/careers/

I'm especially looking to hire Customer Solutions Engineers for the Philly office (http://syapse.com/about/careers/openings/?gh_jid=32512). So if you're on the East Coast and always wanted to join a Bay Area startup, but didn't want to relocate, now is your chance! We're especially interested in people with Python experience. Any experience with healthcare, electronic health records, or genomics is a bonus.

-----


Syapse Inc -- Palo Alto & Philadelphia, PA

Syapse provides a precision medicine data platform that enables laboratories, registries, and providers to use molecular profiling to diagnose and treat patients.

See here for all the open positions: http://syapse.com/about/careers/

I'm especially looking to hire Customer Solutions Engineers for the Philly office. So if you're on the East Coast and always wanted to join a Bay Area startup, but didn't want to relocate, now is your chance! We're especially interested in people with Python and JS experience. Any experience with healthcare, electronic health records, or genomics is a bonus.

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LOVED these as a kid. I loved building all sorts of fans and paddleboat things. Only bummer was that my mom who knew jack about electronics was hyper-paranoid that I was going to electrocute myself playing with them in water. I used to sneak them into the bathroom and put them in the sink behind her back.

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