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SeaFile has a .ignore file with pretty much the same syntax as a .gitignore. And it can also operate on multiple independent directories, has client-side encryption, it's open source and you can host it yourself. So you could actually still use dropbox as backend for the storage, and run both client and server on your machine if you wish. Link: http://seafile.com/en/home/

I've been using seafile for 7 months now and cannot praise it enough. A really nice piece of free software. Hopefully some smart people will do code reviews and improvements in the background to ensure behind the scenes everything is just as nice.

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