I wish those days were long passed. There are definitely still a lot of IE6 users. I recently worked on a project which services the Chinese market. http://www.modern.ie/ie6countdown
Leaving a few million users out of pixel perfection doesn't sound so bad. (And out of those millions, how many will actually stumble upon your web site anyway?)
These 4.4% more might still matter, but the cost-benefit tradeoff looks much different now.