I disagree that homoiconicity is required. Racket is not homoiconic and its macros are pretty powerful (Template Haskell is probably a clearer example but is arguably less powerful). What do you lose by not making the syntax homoiconic? Also what is your definition of homoiconicity?
I thought Racket was homoiconic. You can turn executable code into a data structure by quoting it (e.g. (+ 1 2) is executable code, but '(+ 1 2) is a data structure.) Wikipedia thinks Racket is homoiconic FWIW [ http://en.wikipedia.org/wiki/Homoiconic ]
Racket does not use S-Expressions internally, it uses syntax objects which are not really the same. Furthermore it makes no sense to even ascribe one surface syntax to Racket since it's more than one language really. Also if you ask the main developers of Racket if it's homoiconic they would probably tell you that it's irrelevant (and they would be right). In fact I have this in my IRC logs, "<samth> homoiconicity is a meaningless term that tells you nothing about macros"
It's not meaningless, a lot of people (myself included) use it to talk about programs that can alter their own program in the data structures that they're good at moving around.
In Python, the AST approximates this. Perhaps I'm lax in usage, but I think there's a continuum of homoiconicity - some things (like C) have no language functionality to deal with their own source code. Other languages (like CL) are very good at this, since you write the language in it's own data structures. Other languages (like Python, or Racket) aren't homoiconic, but they approximate what makes homoiconicity special.
Are you saying this approximation makes for less powerful macros? If you are, I find that to be ridiculous, as Racket's macro system is way beyond other Lisps' macro systems.
The syntax objects hold more information about scopes, namespaces and the like than they would were they just datum(s?).