I tend to go full Howard Hughes (not leaving my 2-3 room suite) for a few days, do some limited local exploration, etc. I feel a lot better having a separate bedroom and office. Free breakfast and lounge means effectively unlimited food, although local restaurants, room service, etc are options.
This week I've been at the Le Meridien Bangkok, probably my favorite hotel in town, for 5000 points/night, net, which is essentially $50/night in foregone cash back on credit card purchases, or about $100/night at retail. It cost me $50 to fly here from Singapore, where I couch surfed with friends for a few days, after 10 days in Bali with the girlfriend.
Less risk of fire, norovirus, my hotel is mainly full of nice Japanese people instead of either obnoxious partier spring break types or old dying people, 50M Internet, etc.