Personally, I'm happy that Python 3 is now officially supported, though in practice I haven't had an issues with using Django 1.5 with Python 3.
From personal experience, most of the critical ones are compatible.
Still in progress, but there you go.
There's always the option of just using Upstart or systemd as well.
Of course I'm partial to my new pave project: https://bitbucket.org/mixmastamyk/pave
It is based on fabric, and uses a yaml file to automate it.