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From Inkscape? Little, as SVG is its native format and thus Inkscape's feature set aligns nicely with the capabilities of the format (if used carefully, e.g. using clones instead of copies for identical shapes, etc.). Illustrator, however, will export more or less with a minimum SVG feature set used and for complex drawings that may end up fairly large and fairly inefficient.

Drop shadows and filters in general are a concern. Not so much on desktop browsers nowadays, but in mobile very much.

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