http://bourbon.io/ A simple and lightweight mixin library for Sass
http://inuitcss.com/ a powerful, scalable, Sass-based, BEM, OOCSS framework
http://compass-style.org/ Compass is an open-source CSS Authoring Framework
It seems mediocre for both desktop and mobile, instead of just doing a great design for desktop. What am I missing here? I would love some pointers. Should I just forget about pixel-perfect designs when building responsive websites?
If you're looking for pixel-perfect versions you're best off working with breakpoints and keeping the design rigid up until each breakpoint.
It's more work, but if you really want/need pixel-perfection then it's really the only way to go.