There's a place for "safe spaces" if people are sharing extremely personal stories (e.g. sexual assault, legal issues), but those tend to be done best as small groups anyway - it's a lot harder for a 1000 person auditorium to be a true "safe space".
I'm going to go out on a limb and suggest that there are certain categories of behavior that you would be far less likely to see at an all-female convention than one with men and women. Sexual assault isn't the only thing women worry about— there's a lot more subtle stuff out there that flies right over the head of regular, non-terrible dudes. See some of the stuff Cherie Priest and other ladies in the SF community have posted about lately.
I'm going to go out on a limb and suggest that there are certain categories of behavior that you would be far less likely to see at an all-female convention than one with men and women. Sexual assault isn't the only thing women worry about— there's a lot more subtle stuff out there that flies right over the head of regular, non-terrible dudes. See some of the stuff Cherie Priest and other ladies in the SF community have posted about lately.