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Cancer is such a weird beast that I'm actually not as alarmed by this as it might seem reasonable to be.

Only in the last year or so people have realized that how heterogeneous cancer is. A patient biopsied 10 times from different parts of the cancer turns out to have 10 different (but related) cancers. While such major findings are still occurring about the underlying nature of cancer, it is not surprising that studies are hard to produce; they don't even know which parameters need to be controlled yet to make them reproducible.

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