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When Fabrizio Benedetti of the University of Turin in Italy carried out the above experiment, he added a final twist by adding naloxone, a drug that blocks the effects of morphine, to the saline. The shocking result? The pain-relieving power of saline solution disappeared.

When I read this, I said, out loud, "What the flying farkmipple?"

So does naloxone block placebo effects in general, or only placebo morphine? Inquiring minds want to know.




http://www.nature.com/nature/journal/v306/n5940/abs/306264a0...

Naloxone blocks placebo analgesia in general. I can dig up the referenced papers if you don't have access.

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The placebo opiate link is widely known. Naloxone blocks opiate receptors which blocks placebo effect. Also, children aren't susceptible to a placebo effect.

Check out a good lecture on pain at http://www.youtube.com/watch?v=gQS0tdIbJ0w for more context.

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Thank you, kind sir or madam!

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