Consider the simple case where one wants to look up a value synchronously if one has it in memory, and go get it from storage asynchronously if one doesn't. That's a natural thing to want, but it's problematic in Node. The problem is not syntactic—you can easily write a function that calls back immediately in the one case and asynchronously in the other. It's that sync and async semantics don't compose well, so when you start to do anything a little complicated (e.g. launch N requests and call back when all N have either returned or failed), the two trip over one another. Working in a Lisp that compiles to JS, I had to write some surprisingly complex macros in order to get correct behaviour. I wouldn't dream of writing that JS code by hand.