I use Excel to bulk edit TFS (don't ask) work items. It works by having a plugin that lets you refresh and publish your changes back to the data source. Something like this for regular data would be ideal.
For those who might ask, it's actually useful when you have a series of work items that you want to rapidly change, like the status of a project, deadline, etc. It's a lot less time consuming to add a new row to a sheet rather than having to go through a series of menus and windows to get to where you need.