I have to run out now, but I have a lot more to tell you. Exercise is key, whenever I am in a bad mood I realize that it has been too long since I've exercised. Your body will actually generate new neurons while you are exercising and your brain will release endorphins and other neurotransmitters that increase mood. I know it seems hard to get there if you haven't been in a while, but for a longterm goal and short term boosts of energy, definitely do it. You can try to start with a yoga class or something like that, because at the end of the day yoga is mostly meditation and focus on breath. Meditating is also extremely important in welfare for everyone, especially entrepreneurs and founders. The daily stress of running a startup can not only get you down, but also lead to feeling lost.
I don't know what drugs you are on, but I can recommend some supplements and nootropics that will definitely elevate mood. Try tyrosine.
That said, exercise has been shown to be helpful for depression of every sort (generally at least as effective as drugs, on average).
Exercise is great, go and do that. If it doesn't work, at least you'll put on some muscle when you do get out of it.
I am definitely against any sort of drugs, and I dont think labeling things is particularly helpful, but my suggestion is to get over it. Recognise you can take a beating and survive.
The best advice I can give: change. Change something. Change jobs, hobbies, places. Go looking for new things to excite you again.
I'm about to take my own advice and go on a cycle tour - I'm starting with Holland, then may try the west coast of the US. (It took me a year and a half to get to the point where I even bothered setting goals like that, but it's something good to try and do)
I am pretty anti-pharamcetuicals, but I am very pro-supplement and nutrients. Simply not getting enough of certain amino acids can cause depression or other things. An example is dopamine, which is built from tyrosine in the body. is the neurotransmitter dopamine. The evidence is that it has to do with motivation and not pleasure. I recently wrote an article about that change here ( http://matznerd.com/dopamine-is-not-about-pleasure-anymore-a... ) but the main takeaway is that if you lack the nutrients in your body to make dopamine it can result in depression...
> "in the moment it seems like it will never go away, but the truth is, that it always does."
The truth is, it always does for you. I'm not the same person pre- and post-diagnosis, and even when I'm not feeling down, I never feel quite as 'up' as I used to be. To that end, I don't feel like it's gone away. It's by no means as bad as some other people have it, but I feel like I'm stuck with it now.
Exercise, though, is definitely a good idea, and is a piece of advice I've been given from other depressed friends, my counsellor, and my GP. At the very least, doing a bit of it takes your mind off things, and has the benefit of keeping you in decent shape too.
Personally I don't think someone who is either depressed or feeling blue and is a member here should try and remedy those feelings by immersing themselves in even more startup doom and gloom, or success stories. Take your head out of the job, because it means fuck all compared to your own happiness and wellbeing.
And as has been said, consider change. A change of scenery could offer you some peace of mind.