I was at the grocery store right before the big Powerball drawing and almost got in line to buy a ticket. Then I realized I wouldn't want to win that much money and wouldn't have the slightest clue what to do with it. It would be more stress handling the money than working.
Now, I wouldn't mind starting a business, selling it, and walking away with a few million or 10, it can give me time to grow into my money. But to win a public lottery worth 19's or 100's of millions... I'll pass.