By American Diabetes I mean diabetes due to being overweight. A few years ago, I changed my eating habits, got down to merely chubby, and all traces of diabetes went away. Eventually, changes in work threw my schedule into disarray, I stopped making time to go home and cook and reverted to too much fast food, much of the weight came back, and so did the diabetes.
(I'm not on it, but my wife was after our first kid was born and there was a concern about gestational diabetes).
You have a store of several years of B12 so it can take quite a while before depletion sets in.
Fry: I can't swallow that.
Prof. Farnsworth: Good news! It's a suppository!
There is enormous evidence of health problems caused by high blood sugar. If this applies to cancer too, the actionable plan is to start measuring one's own blood sugar (either daily or with an implant which can do it continuously), and learn to control it. I'm ready to try this myself.
Nothing beats direct measurement / "what gets measures gets fixed".
Statements like this instantly set off my alarm bells. A drug that everybody should be routinely taking? Call me skeptical.
So really I meant that everyone should have health care in the top .1% of healthcare available on the planet, but that's a utopia, not reality.
There's a key difference between drugs and foods. For example, Vitamin C is required for synthesis, metabolism, and enzyme operation . Caffeine simply enhances alertness. Your body will cease to function correctly without Vitamin C; not so without Caffeine (unless you are fostering a dependance)
My favorite example of something that is simultaneously a food, drug, and supplement is the Seville orange. http://en.wikipedia.org/wiki/Bitter_orange
The bitter orange is delicious with stronger orange flavor than a normal orange, particularly in the peel. Most commercially used "natural orange flavor" is derived from bitter orange peels. The bitter orange contains a powerful set of ephedra-like substances, which are quite powerfully mind altering. A single bitter orange is actually uncomfortably stimulating for most people, in the sense that people have enough of a sense for this kind of thing that they stop eating before they consume an entire orange.
But even though sour orange extract is regulated as a supplement, it works as a powerful drug, and an unusually dangerous one at that. It still grows on trees and is very delicious and perhaps available blended in a $15 cocktail near you. Most bartenders don't realize they are adding a stimulant to a drink when they add Seville orange.
We have an old drug that helps diabetes to treat cancer.. The drug costs $.05/pill, for diabetes.
It will be called "Nocan", and feature a $24/pill cost, due to a new patent being granted. *
*Just like Eli Lilly with PMS-PMDD and name change of Prozac to Sarafem. All you need do is bribe FDA for new "disease" name, and you have another 17 yr patent.
There are certainly other ways to compensate people who do this research, but this way maps pretty well to our current laws.
Also widely known as fish oil, and is prescribed for the same reasons fish oil is recommended in supplementation. Only difference is fish oil is marginally less concentrated, much cheaper, doesn't have the 'pharma' tag and isn't prescribed.
In the industry it's known as one of the biggest cash cows for GSK - it's earned them many billions.
Second of all, how does that even work? Metformin is very very widely prescribed.
There are many different ways to patent a drug. Composition patents, formulation patents, use patents, etc.
The problem is that if you get a "use" patent, it only stops other company from promoting the drug for the use you patented. In the case of metformin, it's already available as a cheap generic.
So if a company were to conduct studies proving that it reduced the risk of cancer and got a patent on it, there is nothing to stop a doctor from prescribing the generic version.
So unless a company can find a way to recoup their R&D costs associated with running the trials, they won't bother.
The doctor? He doesn't really make a profit of this and at least over here in Austria, a doctor may prescribe any substance he wants as long as he can argue that it is for the well-being of his patient.
The producer of the diabetes drugs? They don't sell it as a cancer drug.
The apothecary? He's just following the doctor's orders.
That's why you rarely (never?) see a drug company take an old, off-patent drug and try and get a patent for it (in it's original form) on a new disease. Since there is no way to recoup any investment costs, they simply don't make the investment.
What does happen is that drug companies will take an old, off-patent drug and modify it somehow so that it can be patented. They can do that a number of different ways: create a unique formulation of the drug, create a drug-device combination product or try and create a slightly modified (and hopefully improved) version of the original drug.
Under the current system, unless you have a patent (or marketing exclusivity from the FDA) you have no opportunity to recoup any investment you made in the drug.
I'm not 100% sure of this, but I'm pretty sure that this is the way the FDA approval process for drugs work. You can't just 'decide' to prescribe Metformin for cancer one day.
A single drug has to go through the approval process N separate times for N separate applications/diseases.