The most valuable two settings I know for this are:
Now you can use the mouse to resize buffers and click on tabs. You can even click to focus on a buffer and don't need to meta-press your way around when you just want to browse things. Go on, click on topics inside of the help, assign the right click to supertab, navigate NerdTree like the explorer clone it is. Collapse and expand code folds like a 21st century digital boy.
Furthermore, your scrollwheel all of a sudden now scrolls through your document in putty, xterm, screen, rxvt, tmux, iterm; all of them. Yes, total heresy, I know.
The only thing more important than this is doing a visual selection and then doing a :!(any program) like say: fmt, sort, mail, python, rdoc, indent, bc ...
I know what you are thinking; "But kristopolous, this is so easy; it is not possible". Relax my friend, this is unix, you know this.
I always used terminal vim when on Linux, but after I got a macbook (from work - I'd never buy one), I'm pretty happy with MacVim. Give it a shot.
Pretty much everything works out of the box as with the terminal version, you just get a few usability improvements (OS-integrated clipboard, mouse selections create vim selections and vice versa, etc).