I'd use it. I have a UPS Store box for receiving deliveries, but it closes early enough that I can only check it on Saturdays, and it costs as much as recurring semi-weekly BufferBox deliveries (which is more than I would use). A post office box would be worse than that, in closing earlier and refusing private shippers. I have yet to see an Amazon locker in a 7-Eleven; it's a good idea but useless when you order from anyone else (which of course is partly why they can justify the effort). I might consider home deliveries if I had a house on a cul-de-sac with an enclosed porch, but it'd be crazy in an office or apartment building full of strangers (which is, what, 1/3 of Americans?)
I was hoping to see Drop Locker (pivot of Laundry Locker, as I understand it) get into this in San Francisco, but so far they seem to just be looking for partners without having found any.