I get your point about "having more meaning" -- but I'd argue that is true for any business endeavor, not just tech startups. If what I was doing didn't have truly personal meaning for me, there is no way I could stomach the stress.
Maybe I'm overly sensitive because the article seemed to compare the easy hedge fund life to the tough tech start-up life, which I think is a gross over exaggeration in the divergent profile: I believe that they are tremendously similar.
If Dad was an MD he would've said don't become a surgeon, do research and try to change current procedures. At least that's my take on the blog.