Certainly coming here I've realised that I ought to consider non-English languages (particularly Spanish) for web apps. Most folks here in Chile don't speak much English yet their middle class has a growing disposable income. LatAm's power does seem to be growing.
Also some of the companies in our rounds (Round 2+3) were quite inspirational - water purification, classroom neuroscience, human-waste->fertiliser solar cookers, solar powered food cookers, wind farms, safe remittance systems for migrant workers.
I'm most curious to see what Round 4 brings (quad-copters from one I think). Accelerator high-tech is more than Web2.0.