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I'm imagining a $100 device that instead of using any supplies like strips or needles, maybe uses a ultrasonic pulse as a micro-drill to extract a molecular sized droplet of blood to test.

Then it would clean itself using the same ultrasonic pulse emitter.

Or maybe forgo the whole blood deal and somehow use saliva.

It should be possible with saliva but the conditions are finicky. You have to make sure you're reasonably hydrated, but haven't eaten or drank anything in the last 10 minutes, etc.

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