My conclusion, don't do it unless you need it!
Actually, it's a really common position. I used to be extremely conservative about all medicine. One day, I just changed position and figured, "My basic natural-born configuration isn't sacred; 'I' am a product of my internal but also lots of external factors; I can shape both internal and external factors, including nutrition, media, supplements, medicines, technology, culture, location, etc." And after that, a lot of things changed for me. But, I fully understand the position since I used to share it, and I think there's something to it.
Vigorous physical exercise, time in nature, proper hydration, and a clean diet does more for performance and clarity of thought than any medicines or supplements I've found anyways.