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Ointment containing DNA molecules can combat allergic contact dermatitis (medicalxpress.com)
53 points by wglb 9 months ago | hide | past | favorite | 29 comments



I have a severe form of allergic dermatitis that I've been trying to get under control for close to 10 years now. At one point to it so bad I couldn't take a shower without being in excruciating pain, I couldn't sleep, I could barely go through the day. The problem with all of the existing treatments, including the latest generation of monoclonal antibodies and JAK inhibitors is that they downregulate your immune system and they make you more sensitive to allergens if you discontinue the treatment. The only thing that made me better over time was stopping all drugs (including topical ones). It got worse for close to a year, but in 2-3 years my skin "healed". I'm still allergic and do get rashes occasionally, but I'm way less sensitive now.


Have you tried zinc? It sounds like you must have after going through all those medical treatments.


Yes, zinc helped a lot in when the skin was severely inflamed and oozing. After that period passed, I discontinued it as well, because the drier the skin is, the easier it cracks.


So your recommendation is, just let it settle? There is that faction that wants to go for "create artificial oily skin condition" to increase the protective layer. Your opinion on that? Congrats on surviving becoming Marat.


Zinc is usually recommended on an ongoing basis if you have skin problems. Just something to consider.


I've been trying to level up my pop sci medical reading the last few months, and if there's one thing I've learned, it's that our understanding of the human body, how it works and how to fix it, is really still very basic. On the one hand, it's somewhat depressing how little we know and how blunt our tools remain. On the other, it's very exciting just how much of the field remains, frankly, wide open.

There's several medical revolutions just waiting to happen. The next few decades will, hopefully, be very interesting. If I was a young man, I would definitely be getting into biotechnology.


Can I snort it for my hayfever?


Wonder what else we could do with this?

real tan without the risky UV exposure?


Wonder if this might help with mosquito bites also.


Even women can inherit DNA from their many semen depositors.

Well, that being said, I would question the quality of the DNA of such skin cream too!


Y'know, if worded differently, without misogynistic overtones, this could have been a good discussion. Please read the guidelines [0].

[0] https://news.ycombinator.com/newsguidelines.html


I don’t sense any misogyny. Which part are you referring to?


No who you asked but I believe it's the part about "their many semen depositors"


Yep, and "Even women [...]", as if talking about a a curious subset of an eclectic animal species. Beyond that, the transactional wording! Alien archaeologists have some serious linguistic challenges up their sleeve(s).

Sorry you're being downvoted.


You really should be a little more sceptical about what you read.


See my citation for 2023 in other comments


> Even women can inherit DNA from their many semen depositors.

They can? That paper would interest me.



"Jury is still" out might be a bit strong. I can come up with dozens of random postulates, but I can't magically conjure up a jury to hear them out.


idiom


You're saying the "jury is still out" and linking an article that says it's not out and the answer is it's all made up


From the linked article and paper author that’s being referenced:

They describe male DNA found in the brains of women in their study as “most likely” from prior pregnancy with a male fetus and do not conclude or mention that women store DNA from males acquired through intercourse. “In our study as well as others done prior, we merely speculate the establishment of microchimerism through intercourse,” Chan told Reuters. “That is, the possibility exists but it has not been tested (or proven, as the lay person may say).




Uh, that would be a no.

Inheritance doesn't work that way.


In humans maybe not but my koi group spawn all the time. You can have many different sperm fertilizing the same egg.


That's not what they're talking about. The OP was referring to a hoax (which they seem to have fallen for), where a fake news site claimed (incorrectly) that a study had claimed that women carried genetic material (long-term) from men they'd had sex with.


So telegony in humans is totally debunked? Genuinely asking.


Do you refer to your female koi as "women"?




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