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When we decided to have a second child, we'd ruled out every existing disorder that could possibly explain him.

After consultation with our medical team, they concurred that a de novo mutation for Bertrand was a strong possibility.

And, in truth, the conditional probability of de novo mutation for Bertrand was much higher than what actually happened--two independent mutations in the same gene colliding with one another.

If we had known the probability for Victoria was 1/4, we never would have gotten pregnant.

Ignorance was bliss.

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