The only thing I wish is that the keys were in a flat grid rather than staggered, but it seems very very hard to find any keyboard like that, so no biggy. I've considered getting a Kinesis for years now too, but since I got the DAS, I've had no plans of switching any time soon.
I haven't completely worked out my vim bindings since I've been doing a lot of Qt development in QtCreator lately and just used that without vi mode. I use Colemak for my layout so some of the default keys are a little less than optimal, but I also don't want to change them too much. With one or two simple key swaps it seems quite usable though.
On windows (where I don't use vim) I did map alt-gr to some common programmer symbols; mapped caps lock to control and control to backspace. On my laptop I use vanilla colemak though (including caps lock as backspace, though I'm likely going to change that some time).