Yea that's what I mean - the same is true in the SFBA. SJ/South Bay, Berkeley/Oakland/Richmond, the rest of Alameda county, the peninsula, etc are all quite different just like the San Fernando Valley, Inland Empire, Westside, and Orange County near LA.
Air quality in LA is better than it used to be but it's still quite awful. And peak summer temperatures can be brutal.
That said I've lived in both and would take LA over SF any day of the week but the weather has little to do with it