You can write, read, and interact but only for a few hours each day. Pain and fatigue take over the rest of the time. There is also so many little things you take for granted you will not be able to do anymore, or will require assistance to perform. Eating can become a chore, you may have to be regularly plug to some gruesome apparatus, also loss of mobility. Think about the last time you were sick, or injured, think of the worse moment being your new normal.
I personally can`t imagine being happy in those circumstances. I choose #1.
Each person choices should be respected, and people should be better informed on the tradeoff of each choices, which I feel is not the case in our health care system.