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The great thing about bioinformatics is that there's so much data available online for free. Here are some links:

  http://www.ncbi.nlm.nih.gov/ - sequences, papers, and so much more
  http://smd.stanford.edu/ - microarray data
  http://archive.ics.uci.edu/ml/ - not biology related but good data sets to play with R
To navigate NCBI databases and learn file formats, you can read their documentation (http://www.ncbi.nlm.nih.gov/education/) or get any bioinformatics book.

Thanks very much for the helpful links!

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