I'm not an iPad user but it makes a lot of people pretty happy.
Chrome is usually a pleasure to use. Firefox used to be that way, and they are starting to regain my trust again. I feel good about using Firebug as well.
Skype has some irritations, but for the most part it's still marvelous to open up a video chat to fucking Zanzibar whenever I feel like it.
vim is not always easy, but wow is it rock solid.
Upgrading Debian works very well for me at least, thanks to the miracle of apt-get. Debian itself, well, it's not winning usability awards, but still....