In terms of lost years of life the comparison with HIV seems pretty reasonable. Roughly 0.5% of the world population has HIV. I'm not sure how many years of life expectancy HIV costs on average around the world, but conservatively say 40 years. Therefore HIV costs the average person 0.2 years. If CMV impacts 50% of the population and costs 1.1 years, that's a world average of 0.55 years lost per person.