I'm really looking forward to Hyperscript growing more capabilities. I love that it's very natural-language-oriented. I'm really interested in frameworks like this that could make HTML website creation more accessible for regular people. Watching a friend try to build a website with SquareSpace I was thinking... for the amount of effort she put into learning SS's tools and quirks, she could almost have just learned HTML.
I honestly think for the sorts of websites you make in SquareSpace, they shouldn't be. There's no reason that to develop a static website (even with some dynamic elements like a shopping cart) that you should need e.g. a build process to target modern browsers (i.e. consumers in Western economies).
But this is probably me being idealistic. It's why I like things like hyperscript... it feels like we might be _just_ on the cusp of what I'm saying being true.