We handle schema changes very nicely. Our db tool can detect automatically whether a binary and a schema match each other. Most common changes (e.g. field renamings, singletons transformed to lists, etc.) can be handled automatically.
Of course, complete refactorings of subsets of the database may require non-trivial transformation. Opa can't do everything automatically, but it will still check whether the database you obtain at the end of the transformation matches the requirements of your new binary.