I don't like piracy and I will never, ever use any product crippled with DRM. Therefore I read only public domain e books, and they're plenty. If everyone did the same, we'd get rid of this nonsense quickly. Don't encourage them by buying DRM'd ebooks.
I have a Nook and I do not buy any books through B&N.com, only direct from technical publishers that are DRM-free and then load the epub file via USB. In fact I only turn my network connectivity on about once a month to update the clock on the device.