I've been fighting to ban use of interpreted code in production because I hate slow stuff, and like money. So you can use those motivations instead if you like. If you love Python and Ruby, make compilation a first class method of running them.
When I looked at the results seems Swift and C# are pretty good general purpose languages. Interesting to see how bad Typescript compares to JavaScript.
I think the current big deal is GUI support. Seems like they are carefully attacking the problem. If they succeed react is going to be for a world of hurt.