It's a burden for me as a user!
My home theater setup is basically just a Mac connected to a projector. Every button on my Harmony remote runs an Applescript. Many of them start with lines like:
tell application (path to frontmost application) to
I make very heavy use of Applescript for all sorts of things on my computer. It's one of the things that has kept me on Mac over the years, because there is no broadly-supported equivalent on Windows.
I get the sense that no one at Apple uses Applescript much, though, because if they did, they wouldn't have added an impossible-to-disable feature which renders it effectively useless.
Does the Harmony process request Apple automation permissions, and is the Harmony process enabled for it if so? (Whatever the parent process of the scripts you're launching is, i.e. Harmony.app in the chain Remote button -> Harmony.app -> Your Apple.scpt)
Does exiting the Harmony process and all scripts, purging all of your events decisions with `tccutil reset AppleEvents`, and then restarting the Harmony process and running a script result in any improvements?
Is Developer Tools new in Catalina, or do I need to install XCode or some such in order for it to appear? Never saw it in Mojave.
Fwiw, at one point I had a 250 rep bounty on this StackExchange question, and got nothing. :(