Edit: I've been corresponding with Professor Fehren-Schmitz of the Human Paleogenomics lab at UCSC for the past few months and will likely be focusing on improving computational workflows at the lab in the next few months. One recurring theme I've noticed in paleogenomics research is that the people who do the actual paleogenomics aren't always the same people who develop the computational genomics/bioinformatics tools , meaning there might be a bit of a disconnect between those two fields. My understanding of computational paleogenomics is still pretty rough, but it seems to me like a lot of the tools still have a ton of room for improvement.
 Patterson et al., 2012 (Ancient Admixture in Human History)
It's also worth mentioning that (long) before joining David Reich's lab, Nick Patterson worked at GCHQ where he was famously mentor to Clifford Cocks. The story goes that Nick threw an unsolved asymmetric cryptography problem at Cocks and he came back in the morning having invented RSA.
Unless I'm reading it wrong.