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The chemistry is easily the most dangerous aspect for humans and safety protocols have been developed to match. Chances of exposure at the tool-level are probably zero (i.e. on the factory floor you see pictures of). If you are working with bulk chemicals (i.e. one of the support floor(s) below the factory floor), chances are probably higher that you could run into some exposure.

I would say that it is an extremely safe occupation, having worked previously at a major semiconductor manufacturing facility for a few years. A lot of the staff virtually never enter the cleanroom. I personally only ever went in there 3-4 times. The automation is nearly absolute, so most of the effort is spent making sure the computers are doing the right thing. Sending humans into the cleanroom is directly in conflict with the objective of realizing low defect rates, because people are walking particulate factories.




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