Not really, a bunch of apps from the WinRT era are very broken under Windows 10. It’s disappointing given how much from the early 90s still works, but code from 2013 is now totally broken.
Silverlight is where things have started to go downwards wrt long-term stability. But Win32, MFC, and WinForms are still very much alive and well. I mean, WinForms even got .NET Core treatment and high/dynamic DPI support.