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The Effectiveness of Targeted Nutrient Therapy for Mental Illness (2010) [pdf] (semanticscholar.org)
14 points by amelius 31 days ago | hide | past | web | favorite | 1 comment

This may not be a super credible source. Methylation and pyrroluria both raise flags for pseudoscience, and the journal is not a mental health journal but a nutrition journal. The methodology is loosely defined, as the patients were "interviewed for up to 1 hour" to determine the presence of these biochemical markers (?!) and that interview based determination played an outsize role in the intervention performed: "Considerable emphasis was given to the clinical diagnosis, as the biochemical markers are sometimes imprecise and the therapeutic decision may be made on the clinical diagnosis."

Edit: Also, I may have just skimmed too quickly, but did they not comment on any review board or ethics committee signing off on them performing clinical interventions on people with mental health disorders, which in some patients could have caused them to change or stop their prior medication? Big red flag here.

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