Hacker News new | past | comments | ask | show | jobs | submit login

no, when certain conditions lead to certain outcomes like cancer, infections and so on, you cannot really go wrong when results come in early and are so positive they are massively significantly different vs the usual course. effect size.



Indeed you can go very wrong by not doing so. Medical ethics is a balance of risk and benefit, not "What is best for statistical power?" Equipoise is required for trials, and is often a precondition of being able to do studies in these settings.

Heck, a lot of recent work on novel trial designs like stepped-wedge are specifically designed to balance equipoise and statistical needs.




Applications are open for YC Winter 2020

Guidelines | FAQ | Support | API | Security | Lists | Bookmarklet | Legal | Apply to YC | Contact

Search: