Hacker News new | past | comments | ask | show | jobs | submit login

I believe this is the author. https://gero.usc.edu/fasting-conference/professional/andreas...

So let's check a few boxes. Is promoting his own book. This is the WSJ not a medical journal. Mice are not a perfect analog to humans. One study is hilariously small at 69 women. The cancer study is from self reported information. He specializes in alternative medicine, including homeopathy.

Science VS covered this topic a while back. Click on the transcript to get all the references they used when building the episode.

https://gimletmedia.com/shows/science-vs/76hdko/fasting-diet...

There may be something to fasting diet and findings warrant further research. I am willing to wait until it is better understood.




>One study is hilariously small at 69 women. The cancer study is from self reported information. He specializes in alternative medicine, including homeopathy.

>There may be something to fasting diet and findings warrant further research.

You do know Yoshinori Ohsumi won the Nobel Prize in Physiology/Medicine in 2016 for discovering and elucidating mechanisms underlying autophagy right? There isn't really any debate that Fasting/caloric restriction triggers autophagy only in mice not humans, or that autopaghy and its benefits are limited to mice.

What is your standard of proof?


My standard of proof is recommendations from Mayo Clinic, AMA/JAMA. I am not a medical researcher, so I turn to experts.

I am not familiar with Dr. Ohsumi, but looking at a summary of his award in 2016 indicates his research for the genetic and chemical pathways of autophagy. The author of this article is the one linking fasting to autophagy.

My last statement is trying to state that there is room for additional research. Currently the impact (on many things, weight loss, cancer, heart health) of intermittent fasting isn't clear. This is the horrible wishy/washy statement that you get because there is a hypothesis that hasn't been proven/disproven. Personally, I'm ignoring IF until proven otherwise by larger human trials.




Applications are open for YC Winter 2020

Guidelines | FAQ | Support | API | Security | Lists | Bookmarklet | Legal | Apply to YC | Contact

Search: