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It's arguable the Appalachian coal industry wouldn't have been unionized without armed agitation, but that may be unique to the region and the mine owners' eagerness to employ Pinkerton gunmen.

I'd say the last time armed resistance had direct impact on law was the abolition of slavery. Most specifically John Brown's taking of a federal armory in 1859. It didn't end well for Brown, his sons, or the freed slaves involved. It did, however, cause a polarization of public sentiment that accelerated the approach of civil war. Only after the other side was ground to paste was legislation changed nationwide.

To the commentors making a Vietnam analogy - short of storming federal installations ourselves, from whom are we to get the military-grade weaponry to put up any kind of resistance? Russia?

You could just as easily use the American Civil War as a example of armed resistance being ineffective. One of the largest armed resistances in history (the CSA) and it ended up achieving the exact opposite of its aims.

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