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The same way I feel about antivirus in general: they have tons of false positives that turn them into an effective form of censorware (cracks, keygens, demoscene stuff, Hello World programs[1][2], etc.) and are very unlikely to actually protect you from a 0-day. If I happen to have a file I want to run but feel suspicious and can't be bothered analysing it myself, which is a very rare case indeed, I upload it to one of the services that scans it with a dozen or more AVs to see what they think. Even then I will not use my main OS to try it first.

That said, in the context of my original comment, AVs are a bit of a special case because their sole and expected purpose is to detect and remove software they don't like.

[1] https://www.csoonline.com/article/3216765/security/heres-why...

[2] https://stackoverflow.com/questions/22926360/malwarebytes-gi...

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