If by "end of us" you mean human extinction, I'm curious why you think that. Reducing the co2 in a building to whatever level one wants is cheap enough (by bubbling air through water mixed with soda lime or lime) that it seems to me feasible for a few million humans to survive indefinitely even without major advances in technology. (I am assuming that the cost of a co2 measuring device, currently over $1000, could be driven way down before they would be needed in large numbers as part of the machinery to reduce co2 levels inside buildings.)
Wouldn't most food crops would grow much better at 4000 ppm than they do now?
People would be able to go out into the 4000-ppm-co2 outdoors for hours at a time with no obvious serious problems. (I exposed myself to higher levels than that for years by sleeping in a very small room with very low "draftiness". Not recommended of course.)
Co2 at 4000 ppm would kill billions of us and make the survivors miserable and is certainly something I wish for humankind to avoid, but that is different from human extinction.
End of our civilisation. End of us as an industrial society. Perhaps as relevant and historic as the Romans or Ancient Egyptians. I'd prefer to stop long, long before that.
Who knows all the knock on effects of 4,000ppm, I certainly don't except to say it's way beyond the worse case models I've seen. End of much productive work outside. Reduced performance for all. Probably much of the equatorial and tropical simply uninhabitable. We'd be looking at what, 7, 10, 12 degrees? I have no idea. Heaven knows how many reinforcing tipping points will kick in. I don't think we can confidently say it won't result in actual extinction. Even if it probably won't.
We'd lose both ice caps, so something like 60 odd metres of sea level. How many major cities and entire countries does that lose? I've seen maps that at just 4C much of the USA's farm land would be near desert, and the Sahara greening. Unprecedented temperature, habitat and rainfall changes with no idea which species will make it, and which not, maybe many we depend on to eat. How much forced and unwelcome migration? Which prediction is the accurate one? With that energy in the system are we looking at cat 10 super-hurricanes?
Does it matter if it's 0%, 1 or 2%, or even 10% are grubbing out a post-apocalypse zero growth life or whether it's Mad Max, 18th C or bronze age? Unrecognisable. Unpredictable. Survivors would tell fables that their ancestors did it. Knowingly. Maybe some other species gets its chance and does a less idiotic job.
I don't think the difference matters. At all.